eGFR Calculator (CKD-EPI 2021)

eGFR Calculator (CKD-EPI 2021) is evaluated from Age, Sex and Serum Creatinine. The calculation reports eGFR, CKD Stage and Approximate Kidney Function.

Results

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About the eGFR Calculator (CKD-EPI 2021)

eGFR Calculator (CKD-EPI 2021) is treated here as a quantitative relation between Age, Sex and Serum Creatinine and eGFR, CKD Stage and Approximate Kidney Function.

The calculator uses a multi formula configuration. Each reported value is read as a direct evaluation of the stored rules with the declared field formats and units.

Formula basis:
CKD-EPI 2021:
eGFR = 142 x min(Scr/κ, 1)^α x max(Scr/κ, 1)^ - 1.200 x 0.9938^Age x 1.012 (if female)
where κ = 0.7 (female) or 0.9 (male), α = - 0.241 (female) or - 0.302 (male)

Interpret the outputs in the order shown by the result fields. Optional inputs affect only the outputs that depend on those variables.

Formula & How It Works

The calculation applies the following relations exactly as recorded in the metadata:

CKD-EPI 2021:
eGFR = 142 x min(Scr/κ, 1)^α x max(Scr/κ, 1)^ - 1.200 x 0.9938^Age x 1.012 (if female)
where κ = 0.7 (female) or 0.9 (male), α = - 0.241 (female) or - 0.302 (male)

Each output field is produced by substituting the supplied inputs into the relevant relation and then applying the declared rounding or text format.

Worked Examples

Example 1: Normal Kidney Function — 35-Year-Old Male, Scr 0.95

Inputs

age: 35 sex: male scr: 0.95
eGFR: 107 mL/min/1.73m^2. CKD Stage: G1 - Normal or High (>= 90). Approximate Kidney Function: 89%

With Age = 35, Sex = male and Serum Creatinine = 0.95 as the stated inputs, the result is eGFR = 107 mL/min/1.73m^2, CKD Stage = G1 - Normal or High (>= 90) and Approximate Kidney Function = 89%. Each value corresponds to the declared output fields.

Example 2: Early CKD Detection — 60-Year-Old Female, Scr 1.1

Inputs

age: 60 sex: female scr: 1.1
eGFR: 57.5 mL/min/1.73m^2. CKD Stage: G3a - Mildly to Moderately Decreased (45-59). Approximate Kidney Function: 48%

With Age = 60, Sex = female and Serum Creatinine = 1.1 as the stated inputs, the result is eGFR = 57.5 mL/min/1.73m^2, CKD Stage = G3a - Mildly to Moderately Decreased (45-59) and Approximate Kidney Function = 48%. Each value corresponds to the declared output fields.

Example 3: Advanced CKD — 72-Year-Old Male, Scr 3.5

Inputs

age: 72 sex: male scr: 3.5
eGFR: 17.8 mL/min/1.73m^2. CKD Stage: G4 - Severely Decreased (15-29). Approximate Kidney Function: 15%

With Age = 72, Sex = male and Serum Creatinine = 3.5 as the stated inputs, the result is eGFR = 17.8 mL/min/1.73m^2, CKD Stage = G4 - Severely Decreased (15-29) and Approximate Kidney Function = 15%. Each value corresponds to the declared output fields.

Example 4: Near-Normal in Older Woman — Scr 0.7

Inputs

age: 68 sex: female scr: 0.7
eGFR: 94.1 mL/min/1.73m^2. CKD Stage: G1 - Normal or High (>= 90). Approximate Kidney Function: 78%

With Age = 68, Sex = female and Serum Creatinine = 0.7 as the stated inputs, the result is eGFR = 94.1 mL/min/1.73m^2, CKD Stage = G1 - Normal or High (>= 90) and Approximate Kidney Function = 78%. Each value corresponds to the declared output fields.

Common Use Cases

  • Calculate eGFR for chronic kidney disease staging
  • Monitor kidney function with CKD-EPI 2021 equation
  • Evaluate renal function for medication safety
  • Determine CKD stage for nephrology referral planning