Creatinine Clearance Calculator (Cockcroft-Gault)

Creatinine Clearance Calculator (Cockcroft-Gault) is evaluated from Age, Sex and Body Weight. The calculation reports Creatinine Clearance, Normalized CrCl and CKD Stage.

Results

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About the Creatinine Clearance Calculator (Cockcroft-Gault)

Creatinine Clearance Calculator (Cockcroft-Gault) is treated here as a quantitative relation between Age, Sex, Body Weight and Serum Creatinine and Creatinine Clearance, Normalized CrCl, CKD Stage and Ideal Body Weight Used.

The calculator uses a multi formula configuration. Each reported value is read as a direct evaluation of the stored rules with the declared field formats and units.

Formula basis:
CrCl = [(140 - Age) x Dosing Weight (kg)] / (72 x Serum Creatinine mg/dL)
Dosing weight = IBW (or adjusted BW if obese)

Interpret the outputs in the order shown by the result fields. Optional inputs affect only the outputs that depend on those variables.

Formula & How It Works

The calculation applies the following relations exactly as recorded in the metadata:

CrCl = [(140 - Age) x Dosing Weight (kg)] / (72 x Serum Creatinine mg/dL)
Dosing weight = IBW (or adjusted BW if obese)

Each output field is produced by substituting the supplied inputs into the relevant relation and then applying the declared rounding or text format.

Worked Examples

Example 1: Elderly Female — Creatinine 1.2 mg/dL

Inputs

age: 75 sex: female weight_kg: 55 scr: 1.2 height_cm: 160
Creatinine Clearance: 33.5 mL/min. Normalized CrCl: 38 mL/min/1.73m^2. CKD Stage: Stage 3b - Moderately-Severely Decreased (30-44 mL/min). Ideal Body Weight Used: 52.4 kg

With Age = 75, Sex = female, Body Weight = 55 and Serum Creatinine = 1.2 as the stated inputs, the result is Creatinine Clearance = 33.5 mL/min, Normalized CrCl = 38 mL/min/1.73m^2 and CKD Stage = Stage 3b - Moderately-Severely Decreased (30-44 mL/min). Each value corresponds to the declared output fields.

Example 2: Middle-Aged Male — Borderline Renal Function

Inputs

age: 55 sex: male weight_kg: 80 scr: 1.5 height_cm: 175
Creatinine Clearance: 55.5 mL/min. Normalized CrCl: 51.8 mL/min/1.73m^2. CKD Stage: Stage 3a - Mildly-Moderately Decreased (45-59 mL/min). Ideal Body Weight Used: 70.5 kg

With Age = 55, Sex = male, Body Weight = 80 and Serum Creatinine = 1.5 as the stated inputs, the result is Creatinine Clearance = 55.5 mL/min, Normalized CrCl = 51.8 mL/min/1.73m^2 and CKD Stage = Stage 3a - Mildly-Moderately Decreased (45-59 mL/min). Each value corresponds to the declared output fields.

Example 3: Young Adult — Normal Kidney Function

Inputs

age: 28 sex: male weight_kg: 75 scr: 0.9 height_cm: 178
Creatinine Clearance: 126.5 mL/min. Normalized CrCl: 115 mL/min/1.73m^2. CKD Stage: Stage 1 - Normal or High (>= 90 mL/min). Ideal Body Weight Used: 73.2 kg

With Age = 28, Sex = male, Body Weight = 75 and Serum Creatinine = 0.9 as the stated inputs, the result is Creatinine Clearance = 126.5 mL/min, Normalized CrCl = 115 mL/min/1.73m^2 and CKD Stage = Stage 1 - Normal or High (>= 90 mL/min). Each value corresponds to the declared output fields.

Example 4: Obese Patient — Adjusted Body Weight

Inputs

age: 60 sex: female weight_kg: 110 scr: 1 height_cm: 165
Creatinine Clearance: 73.8 mL/min. Normalized CrCl: 67.5 mL/min/1.73m^2. CKD Stage: Stage 2 - Mildly Decreased (60-89 mL/min). Ideal Body Weight Used: 56.9 kg

With Age = 60, Sex = female, Body Weight = 110 and Serum Creatinine = 1 as the stated inputs, the result is Creatinine Clearance = 73.8 mL/min, Normalized CrCl = 67.5 mL/min/1.73m^2 and CKD Stage = Stage 2 - Mildly Decreased (60-89 mL/min). Each value corresponds to the declared output fields.

Common Use Cases

  • Estimate kidney function from serum creatinine
  • Calculate CrCl for medication dosing adjustments
  • Screen for chronic kidney disease
  • Determine need for renal dose adjustment in clinical practice